Index

A-beta fiber neurons
A-delta fiber neurons
acetaminophen
acetylcholine ,
action potential
ion flow
propagation
acute pain
adrenocorticotropic hormone (ACTH)
affect
aggressive behavior ,
agitation ,
agnosia
agomelatine ,
agonists , ,
akathisia , ,
alcohol abuse , , , , , ,
reduced risk drinking
alcohol withdrawal syndrome
allodynia
alpha 1 adrenergic receptor antagonists , ,
alpha 2 adrenergic receptor agonists
alprazolam
Alzheimer’s disease
biomarkers ,
comorbidity
depression in
diagnosis , ,
treatment , , ,
amantadine ,
American Academy of Pediatrics (AAP)
American Heart Association (AHA)
amitriptyline
amphetamine ,
amygdala , , ,
anhedonia , ,
antagonists
anterior cingulate cortex ,
anticholinergic rebound
antidepressants
bipolar disorder
in pregnancy
overdose
side effects , , ,
individual drugs
antioxidants
antipsychotics , ,
atypical , ,
characteristics
polypharmacy
side effects , , , , , , ,
individual drugs
anxiety attacks
anxiety disorder See
apathy
aphasia
apoptosis
apraxia
aripiprazole , , , , , , ,
asenapine , ,
atomoxetine , , , , , ,
attention deficit hyperactivity disorder (ADHD) ,
and substance abuse

328
cortical brain development ,
diagnosis
dopamine transporter defect
drug interactions
inattentive subtype ,
liver impaired patients
treatment , , , ,
atypical antipsychotics , ,
individual drugs
auditory hallucinations ,
axonal zone

bacteriuria in dementia
“bath salts”
benztropine
beta amyloid
binge eating disorder
biomarkers in Alzheimer’s disease ,
bipolar disorder
children
disease course
pregnancy
treatment , , , , , , , , ,
bipolar storm
brain-derived neurotrophic factor (BDNF) ,
breast secretions
buprenorphine ,
bupropion , ,
teratogenicity
buspirone
butyrylcholinesterase

C fiber neurons
C reactive protein
caffeine
calcium channels
blocking
voltage-sensitive ,
calcium, action potential
cannabidiol
cannabinoids, synthetic ,
carbamazepine
cardiac arrhythmia
catechol-O-methyltransferase (COMT) ,
cheese, tyramine in
chemical neurotransmission
chlordiazepoxide
chlorpromazine
cholinesterase inhibitors ,
dementia , , ,
chronic obstructive pulmonary disease
circadian rhythms
disruption of
phase advanced
See also
citalopram ,
clomipramine
clonazepam
clonidine
clozapine , , ,
cocaine addiction
codeine
cognitive behavioral therapy
cognitive function , ,
cognitive restructuring
compulsivity ,
congenital heart defects
corticotropin releasing hormone (CRH)
cortisol
Crh gene
cyclobenzaprine ,
cycloserine , , , ,
CYP450 1A2
CYP450 2D6 ,
CYP450 3A4 ,
cytokines
in depression

deacetylation
dementia ,
329
differential diagnosis
specific types
dendritic membrane
depression
and Alzheimer’s disease
late-onset
See also
diabetic peripheral neuropathy
diazepam , ,
disulfiram
dizziness
donepezil , , ,
dopamine
and depression
deficiency
natural highs
dopamine D2 receptors
blockade , ,
prolactin release
upregulation
dopamine transporter defect
dorsolateral prefrontal cortex , ,
doxepin ,
duloxetine , , ,
dyskinesia

early life stress
eating disorders
eicosapentaenoic acid
electrical communication
electrocardiogram (ECG)
electroconvulsive therapy
emotional blunting
epigenetics
escitalopram
estazolam
eszopiclone , , ,
excitation-secretion coupling
excitotoxicity
extrapyramidal side effects , ,

fear extinction
fibromyalgia , ,
treatment
treatment-resistant
fluoxetine , , ,
side effects
flupenthixol
fluphenazine
flurazepam ,
fluvoxamine
food addiction
free polysomes
free radicals
frontotemporal dementia

G protein-linked signal transduction cascade
GABA
binding
inactivation
wakefulness promotion
gabapentin , , ,
galactorrhea
galantamine , , ,
gastrointestinal upset
generalized anxiety disorder , , , ,
genetic testing
genetics
glutamate
cytokine effects
hyperactivity
inhibition of release ,
traumatic memory formation
glycine
glycogen synthase kinase 3β
Golgi apparatus
guanfacine

hallucinations
auditory ,
visual
haloperidol , ,
hepatitis, chronic
hippocampus ,
dentate gyrus

330
volume
histamine H1 receptors
blockade , ,
sleep-wake cycle ,
histamine H2 receptors in sleep–wake cycle
histamine H3 receptors in sleep–wake cycle
histamine inactivation
histones
5-HT See
Huntington’s disease
hydrocodone ,
hyperactivity
hyperalgesia
hypersomnia ,
hypertensive crisis
hypnotics
tolerance to
hypomania , , ,
hypothalamic pituitary adrenal (HPA) axis
hypothalamus

ibuprofen
iloperidone , , ,
impulsivity , , ,
indoleamine 2,3 dioxygenase
inflammatory markers ,
inositol monophosphatase
insomnia , , , ,
interleukin 1
interleukin 6 ,
International Society for Bipolar Disorders (ISBD) ,
ion channels
ligand-gated , , ,
voltage-sensitive , , , ,

ketamine ,
kynurenine

lamotrigine , , , ,
levetiracetam ,
Lewy body dementia
ligand-gated ion channels , , ,
lisdexamfetamine
lithium , , , ,
mechanism of action
monitoring
pregnancy
liver impairment
lurasidone , ,

magnesium
maintenance of wakefulness tests
major depressive disorder , , , ,
inflammatory markers ,
natural therapies
perimenopausal patients
SSRI-induced indifference
symptoms
treatment , , , , ,
treatment-resistant , , , , ,
mania , ,
MAOIs , ,
marijuana abuse , ,
melatonin , , ,
receptor agonists
memantine , ,
menopause
meperidine
mesolimbic pathway
metabotropic glutamate receptors
methamphetamine
methylation
methylenedioxypyrovalerone
methylenetetrahydrofolate reductase (MTHFR)

331
L-methylfolate
methylphenidate , ,
migraine
mild cognitive impairment ,
milnacipran ,
mirtazapine
mitochondria
dysfunction
modafinil ,
monoamine oxidase inhibitors See
monoamine projections
mood stabilizers
morphine
multiple sleep latency tests
muscarinic M1 receptor blockade ,
muscarinic M3 receptor blockade

naltrexone ,
narcolepsy ,
natural highs
N-back test
necrosis
neurogenesis ,
neuropathic pain
diabetic peripheral neuropathy
treatment
See also
neuropeptide inactivation
neurotransmission
excitation-secretion coupling
retrograde
signal integration
synaptic , ,
volume
neurotransmitters
individual neurotransmitters
nicotine replacement therapy
nitric oxide synthetase
NMDA receptors
activation
blockade ,
N-methyl-D-aspartate See
nociception , ,
norepinephrine
and depression
nociceptive pathways
nucleus accumbens

obsessive compulsive disorder ,
olanzapine , , , , , , , ,
olanzapine-fluoxetine ,
olfactory bulb
omega 3 fatty acids
opioids
addiction , ,
orbital frontal cortex , ,
and aggressive symptoms
orexin
orexin antagonists ,
orthostatic hypotension

pain
acute
chronic , ,
fibromyalgia See
neuropathic , ,
paliperidone , ,
panic disorder
parabrachial nucleus
parkinsonism ,
paroxetine , , ,
teratogenicity
periaqueductal gray
periodic limb movements
persistent pulmonary hypertension of the newborn (PPHN)
pharmacokinetics ,
pipothiazine
polysomnography
positive affect, reduced
positive allosteric modulation
postnatal adaptation syndrome (PNAS)
postsynaptic neuron

332
post-traumatic stress disorder (PTSD) , , , ,
prophylaxis
treatment
treatment-resistant ,
potassium, action potential
prefrontal motor cortex ,
pregabalin , , , , , ,
pregnancy
antidepressant use
bipolar disorder
presynaptic reuptake transporters
presynaptic transporters
presynaptic zone
prolactin
propranolol
protein kinase C
psychosis
and synthetic cannabinoids
See also
pyramidal glutamate neurons

quazepam
quetiapine , , , , , , , , , , , ,
pregnancy
quinolinic acid

ramelteon ,
receptors
dopamine , ,
NMDA
serotonin
upregulation
recovery
recurrence
relapse
remission
reserpine
response to treatment
retrograde neurotransmission
ribosomes, membrane-bound
risperidone , , , , ,
rivastigmine ,
rough endoplasmic reticulum

safety therapy
schizophrenia
cognitive function
drug switching
treatment , , , , , , , , ,
second messengers
sedation
selective attention ,
selective serotonin reuptake inhibitors See
selegiline ,
serotonergic pathways
serotonin
and depression
cytokine effects
inactivation
neurotransmission See
nociceptive pathways
serotonin 1A receptor agonists
serotonin 2A receptors
blockade , , , ,
prolactin release
serotonin 2C receptor blockade , , ,
serotonin 3 receptor blockade
serotonin 6 receptor blockade
serotonin 7 receptor blockade
serotonin and norepinephrine reuptake inhibitors See
serotonin transporter (SERT)
blockade
genetic variants
sertraline
sexual dysfunction ,
shift work disorder
signal transduction cascade ,
G protein-linked
sleep cycle disorders
early waking

333
insomnia , , , ,
narcolepsy ,
periodic limb movements
shift work disorder
sleep hygiene
smoking cessation ,
SNRIs , ,
dementia
major depressive disorder
individual drugs
sodium
action potential
sodium channels
voltage-sensitive , ,
soma
spice ,
SSRIs
dementia
effects on pain ,
indifference induced by
major depressive disorder , , , ,
obsessive compulsive disorder
serotonin syndrome
individual drugs
stimulants
striatum
Stroop task
substance abuse , ,
specific substances
substantia nigra ,
suicidal ideation
supplementary motor area
suprachiasmatic nucleus , , ,
sustained attention
suvorexant
synaptic neurotransmission , ,
synaptogenesis

tardive dyskinesia ,
temazepam ,
teratogenicity ,
tetrabenazine
theophylline
topiramate
transcranial magnetic stimulation
transcription factors
role of
tranylcypromine
trazodone , , , ,
triazolam
tricyclic antidepressants
tryptophan
tumor necrosis factor-alpha ,
tyramine

ultradian cycle
unipolar depression
See also

valproate , , , ,
pregnancy
venlafaxine ,
side effects
ventral striatum ,
ventromedial prefrontal cortex ,
vilazodone
visual hallucinations
vitamin D
voltage-sensitive ion channels , , , ,
volume neurotransmission
vortioxetine

wakefulness, promotion of ,
weight gain
antidepressants ,
antipsychotics ,
bipolar disorder

zaleplon ,
ziprasidone , , ,
zolpidem , ,
zuclopenthixol

 

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