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Stahl's Essential Psychopharmacology Online
In Collaboration With NEI
Stahl's Essential Psychopharmacology

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    • Next Generation Antidepressants:
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  • Methocarbamol
  • Therapeutics
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Methocarbamol

Therapeutics

Brands

• Robaxin

Generic?

Yes

Class

• Skeletal muscle relaxant, centrally acting

Commonly Prescribed for

(FDA approved in bold)
• Musculoskeletal conditions. (Adjunct to rest and physical therapy for relief of acute pain.)
• Muscle spasm

How the Drug Works

• Unclear but might be related to general CNS depression effect

How Long Until It Works

• Pain - 30 minutes or less

If It Works

• Slowly titrate to most effective tolerated dose

If It Doesn't Work

• Increase to highest tolerated dose and consider alternative treatments

Best Augmenting Combos for Partial Response or Treatment-Resistance

• Use other centrally acting muscle relaxants with caution due to potential additive CNS depressant effect
• Can combine with NSAIDs for acute pain

Tests

• None
 

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